If I leave the house, the amps get turned off. If I'm listening to something and then need to do something else with the strong likelihood of putting more music on later, I often leave them on. With the Quickie, I'm a bit more conscious of battery life, so that's another story. The SEX amp, though, sometimes stays on for half a day. I try not to power on and off more than 2-3 in a day. Preferably (and most commonly) only once or twice: in the morning, in the evening.