If you run a Speedballed Crack without the insulators on the TIP50, and you run it long enough, you can really put some stresses on the 6080 and the power transformer. Basically, that half of the 6080 will draw as much current as it can, and the limiting factors end up being how much current the power transformer can supply and/or how much current the tube's cathode can source.
If you have proper voltages at terminals 1 and 5, but not at 7 and 9, but you had the amplifier working before, trying another 6080 may not be a bad idea.