OK, when you get that 270 ohm resistor replaced, you can start by just firing the amp up with the 12AU7 and no 6080. That will take the big board out of the circuit and let you test the small PC boards up front and the 12AU7. The voltages on terminals 1-5 will look mostly correct, with terminals 2 and 4 being a bit on the high side.
Another funky thing that could have happened to your amp would be if the keyway broke off on the bottom of your octal tube, and then it got inserted improperly. This can create all sorts of weird problems and a toasted power supply resistor is certainly an option.