As is mentioned in the FAQ, you'll need to switch a lot more to use higher gain tubes. With something like a 12AX7, assuming you have the Speedball and have modified it for the 12AX7, you would want 30dB of padding at the input of the Crack.
Without the Speedball, you can't get enough loading resistance to use something like a 12AX7 or 12AT7. You might be able to switch the heaters around to use a 6922, which should bias up around 70V on the plate with the stock circuit, and I believe the 6CG7 would work at that point too.