I'm not sure how you're attempting to factor in the 6.3V winding into the analysis of the HV winding performance.
For the HV winding, I have measured the 160V winding to be about 168V unloaded. I also estimate the 160V winding to be about 0.3A AC (not DC!). This corresponds to about 5% regulation, and is enough to populate the fields in PSUD II for the power transformer. I did not find that filling out the source resistance fields was necessary to provide an adequate simulation, YMMV.
I get 407V at the output of the HV power supply in PSUD with a voltage doubler, RC filter with 340 Ohms of series resistance, and a 65mA load.
The manual says that there should be 400V here, so we are 1% off, not too bad. With the heater circuit taxing the power transformer a bit, we would expect that voltage to drop a little.