Actually, I have - some very interesting things to report as a result.
First, the Quickie with either chokes or CCS gives me more gain than necessary. In the case of the chokes, the distortion signature is gain dependent - so turning the pot up not only raised gain, but also raised 2H distortion, leading to a warmer, fatter sound with a collapsed soundstage. I like the sound of my S.E.X. amp so much that I have traditionally preferred going right from the source into the amp, as any (tubed) preamp I stick in between seems to raise the noisefloor, and diminish tiny micro-details in the treble. I want a little bit of gain with no additional "flavor." What I ended up doing is keeping the chokes, as they seem to be able to swing a bigger voltage than the CCS, leading to less noticeable clipping on really loud passages. I then removed the bypass caps, one at a time, as to compare channels. Interestingly, the bypass cap makes the amp have a bit more gain (of course) but also changes the sound signature. I found the bypass to make the amp sound warmer and fatter, especially in the mid-bass to midrange regions, but a bit less clear in the HF region. The amp sounds flatter and more "boring" with just the resistor, presumably due to the additional negative feedback at the cathode. I actually prefer this.
Another experiment was to add some local feedback around the tubes, to decrease noise, and decrease the idiosyncratic nature of particular tubes. 3S4's seem to really vary between example, and I don't like that - I'd rather just plug in a tube and have it sound the same every time. Putting a little bit of plate-to-grid feedback into the mix really cleaned up the amp and is letting through sounds like distant reverb and very tiny details in some recordings - opposite of what some might expect. I suspect this is due to lowering the distortion a bit, as I've found that the typical 2H "tube signature" tends to thicken things up and makes dominant instruments in a recording "stand out" at the expense of ones deeper in the mix. The loop was accomplished via a 1uF film cap in series with a 100k resistor. This seems to give about 3dB of feedback, just enough to flatten things out without making the sound sterile. If anything, I am now hearing the "DHT magic" people talk about. It's almost as though something "lively" or "real" is added to strings and other acoustic instruments, and I've never heard my IDHT tubes do this. I now feel that the preamp in the mix is better than just going straight into the S.E.X. amp - it not only seems to keep the entire bandwidth of my recordings the same, but also adds a little bit of something I can't quite quantify - "magic," if you will? I needed to clean the sound up first to hear it, however. Some of the tubes I have, using the stock circuit, sound WAY too warm and rolled-off for my tastes.
As always, YMMV - keeping in mind that I grew up with solid-state, not tubes! As a result, I suspect that I like a cleaner, flatter, brighter sound than your typical tube guy, but to each their own.