This is as I expected. When the 6080 attempts to operate, it draws excessive current.
Other than a miswire on the large PC board installation, the main cause of a problem like this is the metal on the TIP50 transistors touching the heatsinks.
You should triple check the hardware on these, the shoulder washers and mounting tabs in particular need to be properly placed to keep these parts from shorting out.
-PB
(Your small boards are working perfectly BTW)