Could this be a bad capcitor, rectifier or resistor?
You can temporarily remove the red going to IA on the big board of the offending side, then check the voltage at the 220uF capacitor after the 270 Ohm resistor that is smoking. In my opinion, you will not find an issue with this testing, but it will eliminate the capacitors, rectifier diodes, and resistors in the power supply.
The second time the 270 Ohm resistor blew all LEDs except the one attached to A3 lit until the resistor died.
It's really important not to fixate on which LED's do and don't light up. You have a short in your amplifier that is drawing enough current to blow up a 5 Watt resistor quite quickly. This would tend to be a significant wiring error or two components touching that shouldn't be.
It can often be helpful to post some photos of your build also, in particular the high current C4S board on the offending side, as well as the small PC board in the middle (top and bottom), and the 7 pin and 8 octal socket.
-PB