By all means, set your playback software on the Mac to be full volume, bypass volume control, whatever it may be called. That's the first step in getting the best digital out of a computer. Also, if you're running iTunes, think about switching over to "Play".. I'm not a Mac guy myself but I know a lot of them and this is what they tell me.
If you can bypass the volume control in the dac too, that can only help.
I have no pots or digital volume controls in my main system and the jump in transparency, detail, and dynamics without any mechanical wipers in the system is incredible.
Good luck,
Jim
Jim Rebman -- recovering audiophile
Equitech balanced power; uRendu, USB processor -> Musette DAC -> 5670 tube buffer -> Finale Audio F138 FFX -> Cain and Cain Abbys near-field).
s.e.x. 2.1 under construction. Want list: Stereomour II
All ICs homemade (speaker and power next)